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First astatine-labeled compound shipped in the U.S.
The Department of Energy’s National Isotope Development Center (NIDC) on March 31 announced the successful long-distance shipment in the United States of a biologically active compound labeled with the medical radioisotope astatine-211 (At-211). Because previous shipments have included only the “bare” isotope, the NIDC has described the development as “unleashing medical innovation.”
Thomas K. S. Liang, Chung-Yu Yang, Liang-Che Dai, Fu-Kuang Ko
Nuclear Technology | Volume 153 | Number 2 | February 2006 | Pages 184-196
Technical Paper | Thermal Hydraulics | doi.org/10.13182/NT06-A3699
Articles are hosted by Taylor and Francis Online.
The blowdown of feedwater (FW) line breaks (FWLBs) has been successfully analyzed by using the Appendix K version of RELAP5-3D. To adequately simulate a feedwater blowdown event, one must consider the main steam system, the turbine system, the moisture separator reheaters (MSRs), the main condenser, and the condensate and FW system as all are involved in the modeling scope. The essential components of the simulation scope include the steam header, the high- and low-pressure turbines, the MSR, the FW pump (FWP) turbines, the main condenser, the condensate and booster pumps, the FW heaters of six stages, the steam extraction of seven stages, and the turbine-driven FWPs. All of the components are connected by associated piping as designed.Regarding the FW blowdown analysis, blowdown mass and energy are the two most important parameters to be calculated. Several essential phenomena are involved in this FW blowdown event, which include critical flow at the break and the internal venturi, flashing of FW near the break, runout and coastdown of the FWPs, steam extraction to FW heaters and FWP turbines, flashing of saturated water initially stored inside the FW heater shell sides and MSR drain tanks, energy release from saturated water and system metal, and cold water transportation from the main condenser to the break. All the essential processes involved during FWLB can be well simulated by the advanced Appendix K version of RELAP5-3D. The blowdown analysis calculated by RELAP5-3D/K for the FWLB was contracted to provide a solid basis for the final safety analysis report containment design analysis for the Lungmen advanced boiling water reactor (ABWR) plant. The successful application of RELAP5 for the entire balance-of-plant simulation and associated FW blowdown analysis indicates that the advanced RELAP5 can extend its traditional reactor safety analysis to the entire power conversion system simulation and analysis.