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First astatine-labeled compound shipped in the U.S.
The Department of Energy’s National Isotope Development Center (NIDC) on March 31 announced the successful long-distance shipment in the United States of a biologically active compound labeled with the medical radioisotope astatine-211 (At-211). Because previous shipments have included only the “bare” isotope, the NIDC has described the development as “unleashing medical innovation.”
Constantinos Syros,* Claudio Ronchi, Cinzia Spanó
Nuclear Technology | Volume 94 | Number 2 | May 1991 | Pages 213-227
Technical Paper | Advances in Reactor Accident Consequence Assessment / Nuclear Reactor Safety | doi.org/10.13182/NT91-A34543
Articles are hosted by Taylor and Francis Online.
A semianalytical nonlinear model is described for the calculation of the burst release and release rate of volatile fission product (VFP) from a fuel pellet under steady-state and transient reactor conditions as well as the radial density distribution in the open porosity. The density of the VFP in the porosity channels is assumed to be c(r, t) = φ(r)exp[—LT(r)ω(t)] + Λ-1(t), where L is an analytical function of parameters characterizing the physics and the geometry of the pellet; φ(r) rigorously satisfies the required boundary conditions; and ω(t), the solution of a highly nonlinear differential equation, is a time function (“kinetic time”) that represents the evolution of the density profile. The constant Λ is suitably calculated with the zeroes of the Bessel function Jo(x). The density c(r, t) of the VFP in the open porosity of the pellet is used to find the pressure p(r, t) in the open pores. The integration procedure of the transport equation for different initial and boundary conditions is described. Calculation experiments are presented and discussed.