A review of the plutonium fuel recycle program (1955–1967) did not reveal an economically compelling alternative fuel cycle to slightly enriched uranium, plutonium recycle, or the plutonium breeder. The review included systems involving no chemical separations compared with slightly enriched uranium once through. Nor did freestanding thorium systems appear economic, although synergisms between uranium and thorium may be worth considering, including reduced-density thorium fuels with high fuel durability as an alternative to uranium load following and peaking fuel. The crossed progeny system involving 233U enrichment of uranium in light water reactors (LWRs) and conversion of the plutonium to 233U in fast reactors may offer a method of providing a high-performance denatured LWR fuel for the period beyond the availability of economic slightly enriched uranium.