The effect of nonequilibrium mass transfer on two-phase oxide fuel expansion was studied. An analytical model was applied to fuel expansion tests being planned at Oak Ridge National Laboratory (ORNL) and to whole-core expansion of a uniform bubble in Clinch River Breeder Reactor geometry. Among the parameters varied in the study are the liquid droplet radius (Rp) and the condensation and evaporation coefficients (σ). It was found that allowance for nonequilibrium mass transfer increased the expansion times for the ORNL tests when the ratio of σ/Rp was <1000 m−1. Nonequilibrium mass transfer had little effect on the whole-core expansions until σ/Rp reached unrealistically low values of <10 m−1.