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First astatine-labeled compound shipped in the U.S.
The Department of Energy’s National Isotope Development Center (NIDC) on March 31 announced the successful long-distance shipment in the United States of a biologically active compound labeled with the medical radioisotope astatine-211 (At-211). Because previous shipments have included only the “bare” isotope, the NIDC has described the development as “unleashing medical innovation.”
J. Kópházi, D. Lathouwers, J. L. Kloosterman
Nuclear Science and Engineering | Volume 163 | Number 2 | October 2009 | Pages 118-131
Technical Paper | doi.org/10.13182/NSE163-118
Articles are hosted by Taylor and Francis Online.
This paper presents the development, validation, and results of a three-dimensional, time-dependent, coupled-neutronics-thermal-hydraulic calculational scheme for channel-type molten salt reactors (MSRs). The reactor physics part is based on diffusion theory, extended by a term representing the flow of the fuel through the core. The calculation of the temperature field is done by modeling all fuel channels, which are coupled to each other by a three-dimensional heat conduction equation. For the purpose of validation, the results of the MSR Experiment (MSRE) natural-circulation experiment and the thermal feedback coefficients of the reactor have been calculated and compared.With the aid of a code system developed to implement this scheme, calculations were carried out for the normal operating state of the MSRE and some debris-induced channel-blocking-incident transients. In the case of the MSRE, it is shown that the severity of such an incident strongly depends on the degree of channel blocking and that high-temperature gradients in the moderator can connect thermally the adjacent fuel channels. Results are included for an unblocking transient (i.e., the debris suddenly exits the core, and the fuel flow reverts to the normal operating pattern), and it was demonstrated that during the unblocking large power peaks can be induced.