The distribution of 0–8 M HNO3 between aqueous and 5–100 vol % solutions of TBP in Amsco 125-82 has been measured and used to obtain a quantitative description of this extraction process. Up to ∼5 M aqueous HNO3, a limit arbitrarily chosen because of uncertainties in HNO3 activity coefficients, the data of this report at any particular concentration of TBP in Amsco are accurately described by the equation log [(HNO3)org/{[HNO3]aq(3.75493-(HNO3)org)}] = A + B (HNO3)org, where parentheses refer to concentrations, square brackets to activities, and subscripts org and aq to organic and aqueous phases. The antilogarithms of the constants A for the six TBP-diluent solutions studied can be described as a linear function of , the sum of the mole fractions, and , of water and TBP in the acid-free water-saturated organic phase. These antilogarithms were interpreted as the product K1mγT, where K1m is the thermodynamic equilibrium constant for the extraction reaction and γT is the mean activity coefficient of TBP and TBP·H2O in the acid-free, water-saturated organic phase. As the concentration of TBP in Amsco 125-82 increases from 0 to 100%, K1mγT, in molal units, varies from 0.2 to 1.5. The quantities B of the above equation are proportional to while the product B(HNO3)org is interpreted as log γTN, where γTN is the mean activity coefficient of the species TBP·HNO3 and TBP·HNO3·H2O. The organic phase water and acidity values are consistent with formation of the complexes TBP·H2O, TBP·HNO3, TBP·HNO3·H2O, and TBP·2HNO3.