In a spherical lithium metal assembly with a graphite reflector, the changes in the fission rates of 235U and 238U due to changes in the cross-section sets of the constituent elements of the assembly are calculated. The results are discussed on the basis of experimental data. The fission rate of 235U is found to be most sensitive to changes in the cross-section set of 6Li in the lithium region, while in the graphite reflector, it is most sensitive to that of 12C. The fission rate of 238U is found to be more sensitive to changes in the cross-section sets of the elements in the stainless-steel structure rather than to those of lithium or graphite.