Many reactions involving 6Li are of interest in studies of the performance of charged particle fusion reactor systems. We report measurements of the absolute cross sections for the 6Li(3He, p)8Be reaction from 3 to 6 Me V and include the first estimates of the absolute magnitude of the three-body continuum cross section 6Li(3He, p)2α. The cross sections below 1 MeV are calculated from an s-wave Gamow extrapolation and are used to extract the Maxwell-averaged reaction rate for the 6Li(3He, p)8Be reaction leading to the ground and first excited states of 8Be.