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First astatine-labeled compound shipped in the U.S.
The Department of Energy’s National Isotope Development Center (NIDC) on March 31 announced the successful long-distance shipment in the United States of a biologically active compound labeled with the medical radioisotope astatine-211 (At-211). Because previous shipments have included only the “bare” isotope, the NIDC has described the development as “unleashing medical innovation.”
L. L. Briggs, W. F. Miller, Jr., E. E. Lewis
Nuclear Science and Engineering | Volume 57 | Number 3 | July 1975 | Pages 205-217
Technical Paper | doi.org/10.13182/NSE75-A26752
Articles are hosted by Taylor and Francis Online.
A generalization is made of a previous phase-space finite element approximation of the second-order form of the one-group, two-dimensional neutron transport equation in x-y geometry. Three angular approximations are formulated and compared: continuous piecewise bilinear finite element, piecewise constant finite element, and discrete ordinate. These are incorporated into a unified formalism of discrete ordinate-like equations, enabling the spatial variables to be treated identically using piecewise linear or bilinear finite elements. The resulting equations are solved iteratively by a weighted conjugate gradient method in an improved version of the computer code FENT. Numerical and analytical comparisons of the angular approximations are made, and it is found that both piecewise bilinear and piecewise constant approximations in angle substantially mitigate ray effects. The mitigation is shown to be associated closely with transformation of the hyperbolic discrete ordinate equations to the elliptic operators of the discrete ordinatelike finite element approximations. This transformation is accompanied by the disappearance of the characteristics along the discrete lines of neutron travel, and, hence, by the appearance of physically artificial derivative terms normal to the lines of neutron streaming. These terms grow with the subdomains of the angular finite elements.