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First astatine-labeled compound shipped in the U.S.
The Department of Energy’s National Isotope Development Center (NIDC) on March 31 announced the successful long-distance shipment in the United States of a biologically active compound labeled with the medical radioisotope astatine-211 (At-211). Because previous shipments have included only the “bare” isotope, the NIDC has described the development as “unleashing medical innovation.”
S. Dulla, P. Ravetto, M. M. Rostagno, G. Bianchini, M. Carta, A. D'Angelo
Nuclear Science and Engineering | Volume 149 | Number 1 | January 2005 | Pages 88-100
Technical Paper | doi.org/10.13182/NSE149-88
Articles are hosted by Taylor and Francis Online.
The paper considers some physical aspects of the neutron space kinetics of critical and source-driven subcritical systems. The possibility of introducing some indicators to qualify the spatial nature of neutronic transients is investigated. It is shown theoretically and then proved by numerical examples that the separation of the eigenvalues of the mathematical operator defining the problem can be taken as a good indicator of the importance of space effects in time-dependent conditions. To obtain good physical insight into the phenomena, paradigmatically simple configurations are considered, and whenever possible, a fully analytical approach is used. The presented results evidence the limits of applicability of classic simplified models for transient analyses, such as point kinetics. In a second part, the paper considers the open problem of the choice of the weighting function to be used either for the generation of the kinetic parameters of pointlike models or for the exploitation of quasi-static procedures, analyzing comparatively the effect of different options on the results of transient calculations.