A formula for the uncertainty of core performance parameters based on a combination of the cross-section adjustment and bias factor methods has been derived. The formula is compared with those derived from the cross-section adjustment method and the bias factor method used separately. When the method error correlation is strong between the critical assemblies and a target core, the combined method is superior to the cross-section adjustment method used alone. The combined method is, in general, superior to the bias factor method used alone. Numerical results are presented for the uncertainties of keff, the control rod worth, and the power distribution of a large fast reactor. The combined method yields a smaller uncertainty for the control rod worth calculated in dollar units than the cross-section adjustment method used alone.