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First astatine-labeled compound shipped in the U.S.
The Department of Energy’s National Isotope Development Center (NIDC) on March 31 announced the successful long-distance shipment in the United States of a biologically active compound labeled with the medical radioisotope astatine-211 (At-211). Because previous shipments have included only the “bare” isotope, the NIDC has described the development as “unleashing medical innovation.”
W. L. Dunn, A. M. Yacout, F. O′Foghludha
Nuclear Science and Engineering | Volume 110 | Number 2 | February 1992 | Pages 134-156
Technical Papers | doi.org/10.13182/NSE92-A23883
Articles are hosted by Taylor and Francis Online.
Gamma-ray and neutron dose-equivalent buildup factors are calculated for six common shielding materials in a point-source, infinite-slab, point-detector geometry using a decomposition of the solution to the transport problem into single- and multiple-scatter components. A rigorous solution for the single-scatter component is constructed and a Monte Carlo model for the multiple-scatter component is employed. Simplified models are fit to the calculated buildup factors as functions of slab thickness and source-detector separation, and model constants are evaluated for each of several source energies. Single-scatter and total slab buildup factors are presented, both in tabular form and in graphs that also show the fitted models, for six materials. The models are demonstrated for a sample problem.