The 181Ta(n,xγ) reaction has been measured for neutron energies En = 2 to 100 MeV and for gamma-ray energies Eγ = 2 to 25 MeV using an array of bismuth germanate detectors and the pulsed neutron source at the Los Alamos Meson Physics Facility. The integrated photon production cross section reaches a maximum at ∼ 7.5 MeV. Above 20 MeV, the cross section increases slowly with energy. The angular distributions of the photon production cross sections for different neutron energies are isotropic. At all measured neutron energies the gamma-ray spectra have the simple evaporation form.