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QSA Global, Niowave to collaborate on Ac-225 production using Ra-226
QSA Global, a provider of radioisotope products, and Niowave, a Michigan-based producer of medical radioisotopes, announced that the companies will codevelop a scalable radium purification process using Niowave’s radium-226 processing technology to meet the demand for actinium-225, an alpha-emitter used in the treatment of cancer. According to the companies, the strategic partnership marks a significant advancement in the field of radiopharmaceutical technology, enhancing the supply chain for critical radioisotopes, including Ac-225.
Niowave uses a closed-loop cycle to produce high-purity Ac-225 and other alpha emitters from Ra-226 using a superconducting electron linear accelerator. According to the company’s website, the electron beam impinges on a photon converter to irradiate the Ra-226, inducing a photon-neutron reaction to Ra-225, which decays to Ac-225.
A. H. Kazi, C. R. Heimbach, R. C. Harrison
Nuclear Science and Engineering | Volume 85 | Number 4 | December 1983 | Pages 371-386
Technical Paper | doi.org/10.13182/NSE83-A18384
Articles are hosted by Taylor and Francis Online.
Neutron and gamma-ray tissue kerma and scalar spectrum measurements have been made at the Army Pulse Radiation Division (APRD), Aberdeen Proving Ground, to 1.6 km in air-over-ground geometry from a fission source and are compared to state-of-the-art transport calculations. Measurements have been made by the APRD staff as well as German, Canadian, and French scientists. A variety of integral detectors and differential spectrometers were used. Agreement among the various groups ranges from good to excellent. Calculations have been made in support of shielding programs and in connection with the Hiroshima-Nagasaki dose reevaluation effort. The DOT transport calculations have been performed at the Lawrence Livermore and Oak Ridge National Laboratories, the Defence Research Establishment, Ottawa, and at Science Applications, Inc. Monte Carlo calculations have been performed at Los Alamos National Laboratory. The calculations are generally consistent. Average calculated-to-measured kerma ratios range from 0.83 to 1.27. Calculated-to-measured neutron flux ratios vary from ∼0.6 near 1 keV and ∼0.8 near 5 MeV to ∼1.7 near 0.8 MeV. These spectral differences tend to cancel when determining tissue kerma, raising the possibility that some of the agreement in kerma may be fortuitous. Sources of possible discrepancies are discussed