The potential role of dense plasma focus devices as compact neutron sources for fissile fuel breeding in conjunction with existing fission reactors is considered. It is found that advanced plasma focus devices can be used effectively in conjunction with neutronically efficient fission reactors to constitute “self-sufficient” breeders. Correlations among the various parameters such as the power output and conversion ratio of the fission reactor with the neutron yield and capacitor bank energy of the dense plasma focus device are presented and discussed.