This paper describes the facilities of the Institute of Atomic Energy of the National Nuclear Centre of the Republic of Kazakhstan (IAE NNC RK) (Kurchatov, Kazakhstan) designed to conduct studies on the interaction of hydrogen isotopes with materials of nuclear and fusion reactors with and without neutron irradiation. Experiments with sample irradiation are carried out at the LIANA facility, which is located at the IVG.1M reactor. The VIKA and TiGrA installations are designed to conduct experiments with materials before or after irradiation using the temperature-programmed desorption spectroscopy (VIKA), thermogravimetry, and differential scanning calorimetry (TiGrA) methods. The main results of some experimental studies are also presented.