Isotopes & Radiation

Radiation has benefited mankind in many ways, including its use as an energy source and an indispensable tool in medicine. Since the turn of the 20th century, society has sought ways to harness its potential, while at the same time recognizing that radiological exposures need to be carefully controlled. Out of these efforts, and the work of many dedicated professionals, the principles of justification, optimization, and limitation have emerged as guiding concepts.

Justification means that the use of radiation, from any radiation source, must do more good than harm. The concept of optimization calls for the use of radiation at a level that is as low as reasonably achievable (ALARA). Dose constraints, or limitation, are meant to assist in reaching optimization and protection against harm by setting recommended numerical levels of radiation exposure from a particular source or sources. Together, these three principles form the bedrock of the international radiation protection system that drives decision-­making and supports societal confidence that radiation is being used in a responsible manner.

The National Academies of Sciences, Engineering, and Medicine (NAS) has begun a new webinar series, with the first entry titled “What’s new in low-dose radiation.” The July 22 event kicked off the Gilbert W. Beebe Webinar Series—an extension of the Beebe Symposium, which was established in 2002 to honor the scientific achievements of the late Gilbert Beebe, NAS staff member and designer/implementer of epidemiologic studies of populations exposed to the atomic bombings of Hiroshima and Nagasaki as well as the Chernobyl accident.

The latest season of Amazon’s detective series Bosch premiered recently on its streaming service, Prime. The season opens with the murder of a medical physicist and the theft of radioactive cesium, with plenty of drama following as the protagonist tries to solve the murder and end the “catastrophic threat to Los Angeles.” The show is a work of fiction, but let’s take a closer look at the depiction of radiation to sort out the scientific facts.

The setup: The series stars Titus Welliver as Los Angeles Police Department detective Harry Bosch and Jamie Hector as his partner, Jerry Edgar. The first episode of the sixth and latest season begins late in the evening at a Los Angeles hospital. We are shown a nervous-looking medical physicist as he walks into a laboratory, the camera dramatically focusing on the radiation sign on the door. No one else is around as the medical physicist clears out the lab’s inventory of what we find out later is cesium. The physicist then walks the material out of the hospital without anyone giving him a second look.

The Department of Energy is awarding up to $16 million in new funding to advance research and development of isotope production. The funding opportunity is part of a federal program that produces critical isotopes that are otherwise unavailable or in short supply for U.S. science, medicine, and industry. The effort is aimed at sustaining longstanding U.S. leadership in the vital field of isotope production, research, and development, according to the DOE.

The U.S. healthcare industry is warning that the COVID-19 pandemic may threaten supplies of the medical radioisotope molybdenum-99, whose decay product, technetium-99m, is considered the workhorse isotope in nuclear medicine for diagnostic imaging. The online magazine Radiology Business recently reported that the American Society of Nuclear Cardiology (ASNC) alerted its members on April 1 that it is monitoring supply shortages of Mo-99 “more closely than ever” during the pandemic.