Generative artificial intelligence paired with advanced diagnostic tools could detect potential problems in nuclear power plants and deliver a straightforward explanation to operators in real time. That’s the premise of research out of the Department of Energy’s Argonne National Laboratory, and just one example of the DOE’s increasing exploration of AI applications in nuclear science and technology research. Training and restraining novel AI systems take expertise and data, and the DOE has access to both. According to a flurry of reports and announcements in recent months, the DOE is setting out its plans to ensure the United States can use AI to its advantage to enhance energy security and national security.